Well, the injury updates in San Francisco aren’t getting better as Kyle Shanahan met with reporters today. The Isaac Guerendo update is in, and he is expected to miss a few weeks due to a shoulder injury.
Shanahan: Isaac Guerendo (shoulder) expected to "be out for a few weeks."
— NFL NEWS (@fantasynflnews.bsky.social) August 4, 2025 at 12:15 PM
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